lynx.utils.get_zonation_features

lynx.utils.get_zonation_features(adata_ref, adata_query, n_zones, sample_id='', abundance_test=False, show=False)

Compute zonation (discrete) enriched features

Parameters:

• adata_ref (sc.AnnData) – High-resolution spatial modality

• adata_query (sc.AnnData) – Low-resolution spatial modality

• n_zones (int) – # discrete zones (clusters)

• option (str) – Method to compute discrete zonations (kmeans / piecewise)

• abundance_test (bool) – Whether to compute differentially expressed features per zone per sample

• sample_id (str)

• show (bool)